Gulf Air flight GF972 – a reference to Israel’s telephone country code – took off from Manama airport in the morning bound for Tel Aviv, according to flight-tracking website FlightRadar24.
Bahrain’s foreign minister, Abdullatif Al-Zayani, is leading the delegation.
President Donald Trump’s Middle East envoy, Avi Berkowitz, is also on the flight and is leading a US delegation to Bahrain and Israel, he said on Twitter.
Bahrain and the United Arab Emirates established formal ties with Israel in a US-brokered deal signed at the White House on September 15. Sudan has since said it would also formalise relations with Israel, a former foe.
The foreign minister’s trip to Israel will coincide with a visit there by US Secretary of State Mike Pompeo. They will hold a three-way meeting with Netanyahu, two diplomats briefed on the planning said.